Emmanuel S Akinboye Selected Research

Emetine

12/2017	Anticancer activities of emetine prodrugs that are proteolytically activated by the prostate specific antigen (PSA) and evaluation of in vivo toxicity of emetine derivatives.
6/2016	Iterative design of emetine-based prodrug targeting fibroblast activation protein (FAP) and dipeptidyl peptidase IV DPPIV using a tandem enzymatic activation strategy.
9/2015	Design, synthesis and cytotoxicity studies of dithiocarbamate ester derivatives of emetine in prostate cancer cell lines.
9/2012	Design, synthesis, and evaluation of pH-dependent hydrolyzable emetine analogues as treatment for prostate cancer.

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Emmanuel S Akinboye Research Topics

Disease

6	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 09/2012
4	Neoplasms (Cancer) 01/2019 - 06/2016
1	Carcinoma (Carcinomatosis) 06/2016
1	Breast Neoplasms (Breast Cancer) 06/2016

Drug/Important Bio-Agent (IBA)

4	EmetineIBA 12/2017 - 09/2012
2	maleimideIBA 01/2019 - 01/2018
2	AlbuminsIBA 01/2019 - 01/2018
2	ProdrugsIBA 12/2017 - 06/2016
1	Prostate-Specific Antigen (Semenogelase)IBA 01/2019
1	Niclosamide FDA Link 01/2019
1	ThapsigarginIBA 01/2019
1	Amino Acids FDA Link 01/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	AcidsIBA 01/2018
1	Fluorescein-5-isothiocyanate (FITC)IBA 01/2018
1	Protein Synthesis InhibitorsIBA 12/2017
1	Peptide Hydrolases (Proteases)FDA Link 12/2017
1	Proteins (Proteins, Gene)FDA Link 06/2016
1	Serine Proteases (Serine Protease)IBA 06/2016
1	EnzymesIBA 06/2016
1	Androgen Receptors (Androgen Receptor)IBA 09/2015
1	EstersIBA 09/2015
1	tasquinimodIBA 03/2014
1	quinoline-3-carboxamideIBA 03/2014

Therapy/Procedure

2	Therapeutics 01/2019 - 06/2016
1	Castration 01/2019